Junk DNA in birds may hold key to safe, efficient gene therapy
Published Date: 2/20/2024
Source: sciencedaily.com
For many genetic diseases, disabling or editing a gene using CRISPR is insufficient to overcome the effects of the underlying genetic mutation. A corrective gene needs to be added to the genome to fix the problem. Researchers have discovered a way to use a bird retrotransposon -- a type of junk DNA -- to insert whole transgenes into the human genome in a targeted way that does not risk damaging other genes.